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Alcohol effects on human risk taking

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Abstract

Rationale

Despite a well-established relationship between alcohol and risky behavior in the natural environment, laboratory investigations have not reliably shown acute alcohol effects on human risk-taking.

Objectives

The present study was designed to demonstrate a dose-response relationship between acute alcohol administration and human risk taking. Further, this investigation sought to delineate behavioral mechanisms that may be involved in alcohol-induced changes in the probability of risky behavior.

Methods

Using a laboratory measure of risk taking designed to address acute drug effects, 16 adults were administered placebo, 0.2, 0.4, and 0.8 g/kg alcohol in a within-subject repeated measures experimental design. The risk-taking task presented subjects with a choice between two response options operationally defined as risky and non-risky. Data analyses examined: breath alcohol level (BAL), subjective effects, response rates, distribution of choices between the risky and non-risky option, and trial-by-trial probabilities of making losing and winning risky responses.

Results

The alcohol administration produced the expected changes in BAL, subjective effects, and response rate. Alcohol dose-dependently increased selection of the risky response option, and at the 0.8 g/kg dose, increased the probability of making consecutive losing risky responses following a gain on the risky response option.

Conclusions

Acute alcohol administration can produce measurable changes in human risk-taking under laboratory conditions. Shifts in trial-by-trial response probabilities suggest insensitivity to past rewards and more recent losses when intoxicated, an outcome consistent with previous studies. This shift in sensitivity to consequences is a possible mechanism in alcohol-induced changes in risk taking.

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References

  • Abrams DB, Wilson GT (1983) Alcohol, sexual arousal, and self-control. J Person Soc Psychol 45:188–198

    Article  CAS  Google Scholar 

  • American Psychiatric Association (1994) Diagnostic and statistical manual of mental disorders (DSM-IV, 4th edn). APA Press, Washington D.C.

  • Auta J, Faust WB, Lambert P, Guidotti A, Costa E, Moerschbaecher JM (1995) Comparison of the effects of full and partial allosteric modulators of GABA(A) receptors on complex behavioral processes in monkeys. Behav Pharmacol 6:323–332

    CAS  PubMed  Google Scholar 

  • Bechara A, Dolan S, Hindes A (2002) Decision-making and addiction (part II): myopia for the future or hypersensitivity to reward? Neuropsychologia 40:1690–1705

    Article  PubMed  Google Scholar 

  • Bond AJ (1998) Drug-induced behavioural disinhibition—incidence, mechanisms and therapeutic implications. CNS Drugs 9:41–57

    CAS  Google Scholar 

  • Breiter HC, Aharon I, Kahneman D, Dale A, Shizgal P (2001) Functional imaging of neural responses to expectancy and experience of monetary gains and losses. Neuron 30:619–639

    Article  CAS  PubMed  Google Scholar 

  • Breslin FC, Sobell MB, Cappell H, Vakili S, Poulos CX (1999) The effects of alcohol, gender, and sensation seeking on the gambling choices of social drinkers. Psychol Addict Behav 13:243–252

    Article  Google Scholar 

  • Brodie MS, Shefner SA, Dunwiddie TV (1990) Ethanol increases the firing rate of dopamine neurons of the rat ventral tegmental area in vitro. Brain Res 508:65–69

    CAS  Google Scholar 

  • Byrnes JP (1998) The nature and development of decision making. Erlbaum, Hillsdale, N.J.

  • Byrnes JP (2003) Changing views on the nature and prevention of adolescent risk taking. In: Romer D (ed) Reducing adolescent risk: toward an integrated approach. Sage, Thousand Oaks, Calif.

  • Carlton PL, Siegel JL, Murphree HB, Cook L (1981) Effects of diazepam on operant behavior in man. Psychopharmacology 73:314–317

    CAS  PubMed  Google Scholar 

  • Cherek DR, Steinberg JL, Manno BR (1985) Effects of alcohol on human aggressive-behavior. J Stud Alcohol 46:321–328

    CAS  PubMed  Google Scholar 

  • Cherpitel CJ (1999) Substance use, injury, and risk-taking disposition in the general population. Alcohol Clin Exp Res 23:121–126

    CAS  PubMed  Google Scholar 

  • Cohen J (1960) Chance, skill and luck. The psychology of guessing and gambling. Penguin Press, Baltimore

  • Cutter HCG, Green LR, Harford TC (1973) Levels of risk taken by extraverted and introverted alcoholics as a function of drinking whisky. Br J Soc Clin Psychol 12:83–89

    Google Scholar 

  • Donovan DM, Marlatt GA (1982) Personality subtypes among driving-while-intoxicated offenders: relationship to drinking behavior and driving task. J Consult Clin Psychol 50:241–249

    Article  CAS  PubMed  Google Scholar 

  • Engleman EA, McBride WJ, Li T-K, Lumeng L, Murphy JM (2003) Ethanol drinking experience attenuates (−)sulpiride-induced increases in extracellular dopamine levels in the nucleus accumbens of alcohol-preferring (P) rats. Alcohol Clin Exp Res 27:424–431

    CAS  PubMed  Google Scholar 

  • Ensor T, Godfrey C (1993) Modelling the interactions between alcohol, crime and the criminal justice system. Addiction 88:477–487

    CAS  PubMed  Google Scholar 

  • Eysenck SB, Eysenk HJ (1978) Impulsiveness and venturesomeness: their position in a dimensional system of personality description. Psychol Rep 43:1247–1255

    CAS  PubMed  Google Scholar 

  • Fiorillo CD, Tobler PN, Schultz W (2003) Discrete coding of reward probability and uncertainty by dopamine neurons. Science 299:1898–1902

    Article  CAS  PubMed  Google Scholar 

  • First MB, Spitzer RL, Gibbon M, Williams JBW (1996) Structured clinical interview for DSM-IV axis I disorders: non-patient edition (SCID-NP) (2.0 edn). New York State Psychiatric Institute, New York

  • Fleshler M, Hoffman HS (1962) A progression for generating variable-interval schedules. J Exp Anal Behav 5:529–530

    CAS  Google Scholar 

  • Fromme K, Katz E, D’Amico E (1997) Effects of alcohol intoxication on the perceived consequences of risk taking. Exp Clin Psychopharmacol 5:14–23

    Article  CAS  PubMed  Google Scholar 

  • Fromme K, D’Amico EJ, Katz EC (1999) Intoxicated sexual risk taking: an expectancy or cognitive impairment explanation? J Stud Alcohol 60:54–63

    CAS  PubMed  Google Scholar 

  • Galanter M (1997) Recent developments in alcoholism. Alcohol and violence: epidemiology, neurobiology, psychology, family issues. Plenum Press, New York

    Google Scholar 

  • Glautier S, Bankart J, Rigney U, Willner P (1998) Multiple variable interval schedule behaviour in humans: effects of ethanol, mood, and reinforcer size on responding maintained by monetary reinforcement. Behav Pharmacol 9:619–630

    CAS  PubMed  Google Scholar 

  • Glowa JR, Barrett JE (1976) Effects of alcohol on punished and unpunished responding of squirrel monkeys. Pharmacol Biochem Behav 4:169–173

    Article  CAS  PubMed  Google Scholar 

  • Grant S, Contoreggi C, London ED (2000) Drug abusers show impaired performance in a laboratory test of decision making. Neuropsychologia 38:1180–1187

    Article  CAS  PubMed  Google Scholar 

  • Halpern-Felsher BL, Millstein SG, Ellen JM (1996) Relationship of alcohol use and risky sexual behavior: a review and analysis of findings. J Adolesc Health 19:331–336

    Article  CAS  PubMed  Google Scholar 

  • Hastie R, Dawes RM (2001) Rational choice in an uncertain world: the psychology of judgment and decision making. Sage Publications, Thousand Oaks, Calif.

    Google Scholar 

  • Hindmarch I, Kerr JS, Sherwood N (1991) The effects of alcohol and other drugs on psychomotor performance and cognitive function. Alcohol Alcohol 26:71–79

    CAS  PubMed  Google Scholar 

  • Horwood LJ, Fergusson DM (2000) Drink driving and traffic accidents in young people. Acc Anal Prev 32:805–814

    Article  CAS  Google Scholar 

  • Josephs RA, Steele CM (1990) The two faces of alcohol myopia: attentional mediation of psychological stress. J Abnorm Psychol 99:115–126

    Article  CAS  PubMed  Google Scholar 

  • Julien RM (1995) A primer of drug action, 7th edn. W.H. Freeman and Co., New York

  • Kahneman D, Tversky A (1979) Prospect theory—analysis of decision under risk. Econometrica 47:263–291

    Google Scholar 

  • Kahneman D, Tversky A (1984) Choices, values, and frames. Am Psychol 39:341–350

    Article  Google Scholar 

  • Lane SD, Cherek DR (2000a) Risk aversion in human subjects under conditions of probabilistic reward. Psychol Rec 50:221–234

    Google Scholar 

  • Lane SD, Cherek DR (2000b) Analysis of risk taking in adults with a history of high risk behavior. Drug Alcohol Depend 60:179–187

    Article  CAS  PubMed  Google Scholar 

  • Lane SD, Cherek DR (2001) Risk taking by adolescents with maladaptive behavior histories. Exp Clin Psychopharmacol 9:74–82

    CAS  PubMed  Google Scholar 

  • Lanza-Kaduce L, Bishop DM, Winner L (1997) Risk/benefit calculations, moral evaluations, and alcohol use: exploring the alcohol-crime connection. Crime Delinq 43:222–239

    Google Scholar 

  • Liguori A, D’Agostino RB Jr, Dworkin SI, Edwards D, Robinson JH (1999) Alcohol effects on mood, equilibrium, and simulated driving. Alcohol Clin Exp Res 23:815–821

    CAS  PubMed  Google Scholar 

  • Lopes LL (1987) Between fear and hope: the psychology of risk. In: Berkowitz L (ed) Advances in experimental social psychology. Academic Press, New York, pp 255–295

  • Martin SE (2001) The links between alcohol, crime and the criminal justice system: explanations, evidence and interventions. Am J Addict 10:136–158

    Article  CAS  PubMed  Google Scholar 

  • Marx BP, Gross AM, Adams HE (1999) The effect of alcohol on the responses of sexually coercive and noncoercive men to an experimental rape analogue. Sex Abuse 11:131–145

    CAS  PubMed  Google Scholar 

  • McMillen DL, Wells-Parker E (1987) The effect of alcohol consumption on risk-taking while driving. Addict Behav 12:241–247

    Article  CAS  PubMed  Google Scholar 

  • McMillen DL, Smith SM, Wells-Parker E (1989) The effects of alcohol, expectancy, and sensation seeking on driving risk-taking. Addict Behav 14:477–483

    Article  CAS  PubMed  Google Scholar 

  • Meier SE, Brigham TA, Ward DA, Meyers F, Warren L (1996) Effects of blood alcohol concentrations on negative punishment: implications for decision making. J Stud Alcohol 57:85–96

    CAS  PubMed  Google Scholar 

  • Mellers BA, Schwartz A, Cooke AD (1998) Judgment and decision making. Annu Rev Psychol 49:447–477

    Article  CAS  PubMed  Google Scholar 

  • Mello NK, McNamee HB, Mendelson JH (1968) Drinking patterns of chronic alcoholics: gambling and motivation for alcohol. Psychiatr Res Rep 24:83–118

    CAS  Google Scholar 

  • Milgram GG (1993) Adolescents, alcohol and aggression. J Stud Alcohol Suppl 11:53–61

    CAS  PubMed  Google Scholar 

  • Miller DC, Byrnes JP (1997) The role of contextual factors and personal factors in children’s risk taking. Dev Psychol 33:814–823

    Article  CAS  PubMed  Google Scholar 

  • Muntaner CC, Higgins STS, Roache JDJ, Henningfield JEJ (1991) Ethanol decreases responding on behavior maintained under concurrent schedules of both positive reinforcer presentation and avoidance in humans. Behav Pharmacol 2:47–56

    PubMed  Google Scholar 

  • Patton JH, Stanford MS, Barratt ES (1995) Factor structure of the Barratt Impulsiveness Scale. J Clin Psychol 51:768–774

    CAS  PubMed  Google Scholar 

  • Rachlin H (1990) Why do people gamble and keep gambling despite heavy losses? Psychol Sci 1:294–297

    Google Scholar 

  • Rachlin H (2000) The science of self-control. Harvard University Press, Cambridge, Mass.

  • Rachlin H, Frankel M (1969) Choice, rate of response, and rate of gambling. J Exp Psychol 80:444–449

    Google Scholar 

  • Rachlin H, Logue AW, Gibbon J, Frankel M (1986) Cognition and behavior in studies of choice. Psychol Rev 93:33–45

    Article  Google Scholar 

  • Schmitt WA, Brinkley CA, Newman JP (1999) Testing Damasio’s somatic marker hypothesis with psychopathic individuals: risk takers or risk averse? J Abnorm Psychol 108:538–543

    Article  CAS  PubMed  Google Scholar 

  • Seto MC, Barbaree HE (1995) The role of alcohol in sexual aggression. Clin Psychol Rev 15:545–566

    Article  Google Scholar 

  • Shafir E, Tversky A (1995) Decision making. In: Smith EE, Osherson DN (eds) Thinking: An invitation to cognitive science. MIT Press, Cambridge, Mass., pp 77–100

  • Shipley-Boyle B (1967) The Shipley Institute of Living Scale. Western Psychological Services, Los Angeles, Calif.

  • Slovic P (1969) Differential effects of real versus hypothetical payoffs on choices among gambles. J Exp Psychol 80:434–437

    Google Scholar 

  • Slovic P, Lichtenstein S (1968) Relative importance of probabilities and payoffs in risk taking. J Exp Psychol 78:1–17

    Google Scholar 

  • Snedecor GW, Cochran WG (1980) Statistical methods (7th edn). The Iowa State University Press, Ames, Iowa

  • Taylor SP, Chermack ST (1993) Alcohol, drugs, and human physical aggression. J Stud Alcohol 11:78–88

    CAS  Google Scholar 

  • Teger AI, Katkin ES, Pruitt DG (1969) Effects of alcoholic beverages and their congener content on level and style of risk taking. J Person Soc Psychol 11:170–176

    CAS  Google Scholar 

  • Testa M, Collins LR (1997) Alcohol and risky sexual behavior: event-based analyses among a sample of high-risk women. Psychol Addict Behav 11:190–201

    Article  Google Scholar 

  • Thompson T, Schuster CR (1968) Behavioral pharmacology. Prentice-Hall, Englewood Cliffs, N.J.

  • van Haaren F (1993) Schedule-controlled behavior: positive reinforcement. In: van Haaren F (ed) Methods in behavioral pharmacology. Elsevier, Amsterdam, pp 81–99

  • Vogel RA, Frye GD, Wilson JH, Kuhn CM, Kuepke KM, Mailman RB, Mueller RA, Breese GR (1980) Attentuation of the effects of punishment by ethanol: comparisons with chlordiazepoxide. Psychopharmacology 71:123–129

    CAS  PubMed  Google Scholar 

  • Vogel-Sprott M (1967) Alcohol effects on human behavior under reward and punishment. Psychopharmacologia 11:337–344

    CAS  PubMed  Google Scholar 

  • Zachary RA, Paulson MJ, Gorsuch RL (1985) Estimating WAIS IQ from the Shipley Institute of Living Scale using continuously adjusted age norms. J Clin Psychol 41:820–831

    CAS  PubMed  Google Scholar 

  • Zarr JH (1984) Biostatistical analysis (2nd edn). Prentice-Hall, New Jersey

  • Zuckerman M (1979) Sensation seeking: beyond the optimal level of arousal. Erlbaum, Hillsdale, N.J.

    Google Scholar 

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Acknowledgements

This research was supported by NIDA grant DA R01 15392. We thank Dr. Kim Fromme for generously providing psychometric instruments, and Jennifer Sharon, Sally Chee, and Ehren Bradbury for their assistance in conducting the experiments.

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Authors and Affiliations

  1. Psychiatry and Behavioral Sciences, The University of Texas Health Science Center—Houston, 1300 Moursund Street, Houston, TX 77030, USA

    Scott D. Lane, Don R. Cherek, Cynthia J. Pietras & Oleg V. Tcheremissine

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  1. Scott D. Lane
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  2. Don R. Cherek
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Correspondence to Scott D. Lane.

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Lane, S.D., Cherek, D.R., Pietras, C.J. et al. Alcohol effects on human risk taking. Psychopharmacology 172, 68–77 (2004). https://doi.org/10.1007/s00213-003-1628-2

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